POLYMORPHES ANHYDRES DE NITRATE DE MÉTHYLE [(2R,3S,4R,5R)-5-(6- (CYCLOPENTYLAMINO)-9H-PURIN-9-YLE)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YLE)]ET PROCESSUS DE PRÉPARATION DE CEUX-CI

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专利权人:

INOTEK PHARMACEUTICALS CORPORATION

发明人:

MCVICAR, WILLIAM, K.

申请号：

EP13741502

公开号：

EP2807178A4

申请日:

2013.01.25

申请国别(地区):

EP

年份:

2015

代理人:

摘要：

The present invention provides a novel anhydrous polymorph form of [(2R,3S,4R,5R) -5-(6-(cyc]opentylamino)-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)]methyl nitrate (Compound A). The present invention also provides processes for preparation of the anhydrous polymorphic form of compound A, compositions containing the polymorph form, and use of the polymorph form for the preparation of ophthalmic compositions.

来源网站：

中国工程科技知识中心

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http://www.ckcest.cn/home/