THE COUNCIL OF THE QUEENSLAND INSTITUTE OF MEDICAL RESEARCH
发明人:
COREY SMITH,RAJIV KHANNA
申请号：
BR112018072305
公开号：
BR112018072305A2
申请日:
2017.05.25
申请国别(地区):
BR
年份:
2019
代理人:
摘要：
The present invention relates to methods and compositions related to selection t-cells and / or individuals for adoptive immunotherapy based on the expression of one or more selected biomarkers from granzyme b, granzyme k, perforin, cd8, pd-1, thymus 3, lag-3, ctla-4, ct107a, ifng, il-2, tnf and cd4.a presente invenção refere-se a métodos e composições relacionados às células t de seleção e/ou indivíduos para imunoterapia adotiva com base na expressão de um ou mais biomarcadores selecionados dentre granzima b, granzima k, perforina, cd8, pd-1, tim-3, lag-3, ctla-4, ct107a, ifng, il-2, tnf e cd4.
