THE COUNCIL OF THE QUEENSLAND INSTITUTE OF MEDICAL RESEARCH
发明人:
Rajiv KHANNA,Corey SMITH
申请号：
MX2018013963
公开号：
MX2018013963A
申请日:
2017.05.25
申请国别(地区):
MX
年份:
2019
代理人:
摘要：
Provided herein are methods and compositions related to the selection T cells and/or subjects for adoptive immunotherapy based on the expression of one or more biomarkers selected from granzyme B, granzyme K, perforin, CD8, PD-1, TIM-3, LAG-3, CTLA-4, CD107a, IFNg, IL-2, TNF and CD4.Se proporcionan en la presente metodos y composiciones relacionados con la seleccion de celulas T y/o sujetos para inmunoterapia adoptiva basada en la expresion de uno o mas biomarcadores seleccionados de granzima B, granzima K, perforina, CD8, PD-1, TIM-3, LAG-3, CTLA-4, CD107a, IFNg, IL-2, TNF y CD4.
