The invention provides ''a promoter for generation of glutathione obtaining ingredients from natural objects with high safety'', and provides ''pharmaceuticals, foodstuff, or cosmetics comprising the promoter for generation of glutathione and with glutathione generation promoting effect''. The promoter for generation of glutathione comprises a plant extract comprising Saussurea species, in particular an extract selecting from more than one plant of Saussurea involucrata (Kar.et Kir.) Sch.Blp.), Saussurea medusa Maxim.) and Saussurea laniceps Hand.-Mazz. as active ingredients.提供一種[使用由安全性高的天然產物得到的成分的麩胱甘肽產生促進劑]。而且提供一種[含有該麩胱甘肽產生促進劑,具有麩胱甘肽產生促進作用的醫藥品、食品或化妝料]。含有以來自屬於青木香(Saussurea)屬的植物的萃取物,特別是來自由新疆雪蓮(Saussurea involucrate(Kar.et Kir.)Sch.Blp.)、水母雪蓮(Saussurea medusa Maxim.)及綿頭雪蓮(Saussurea laniceps Hand.-Mazz.)組成的群中選擇的一種以上的植物的萃取物為有效成分的麩胱甘肽產生促進劑。