The pirimijinon chemical compound which possesses formula (i), the recipe and use are disclosed. Although the said chemical compound is the inhibiter of HMG-CoA reductase, it depends and possesses anti- virus activity, the circulatory organ and the brain blood vessel disease, the old age characteristic acknowledgment symptom, true characteristic diabetes, the bone roughly remedies the pore symptom and the tumor, Shank it does the immunity function in the patient, it is useful, although it remedies and prevents the disease which accompanies the especially high fat blood and it is useful.式(I)を有するピリミジノン化合物、その調製法及び用途が開示される。該化合物はHMG-CoAレダクターゼの阻害剤であり、よって抗ウイルス活性を有し、循環器及び脳血管疾患、老年性認知症、真性糖尿病、骨粗鬆症及び腫瘍を治療し、患者における免疫機能を亢進するのに有用であり、特に高脂血を伴う疾患を治療及び予防するのに有用である。