COMPOSÉS POUR CIBLER DES ISOFORMES DE RÉCEPTEUR D'HORMONE THYROÏDIENNE ALPHA ET LEURS PROCÉDÉS D'UTILISATION

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专利权人:

McMaster University

发明人:

申请号：

EP16877052.7

公开号：

EP3393466A4

申请日:

2016.12.22

申请国别(地区):

EP

年份:

2019

代理人:

摘要：

Two isoforms of thyroid receptor alpha (THRα1 and THRα2) have been found to be associated with the growth of cancer. Use of inhibitors of THRα1 (Formula I) and/or agonists of THRα2 (Formula II) in the treatment of such cancers is disclosed. Treatment of other disorders associated with such receptors is also contemplated, as is the use of diagnostic methods for predicting therapeutic outcomes based on the levels of expression of THRα1 and THRaα2 in a tissue sample.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/