Factor VII polypeptides that are modified and uses thereof

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专利权人:

CATALYST BIOSCIENCES; INC.

发明人:

Edwin L. Madison,Christopher Thanos

申请号：

US13987492

公开号：

US09476037B2

申请日:

2013.07.30

申请国别(地区):

US

年份:

2016

代理人:

摘要：

Modified factor VII polypeptides and uses thereof are provided. Such modified FVII polypeptides include Factor VIIa and other forms of Factor VII. Among modified FVII polypeptides provided are those that have altered activities, typically altered procoagulant activity, including increased procoagulant activities. Hence, such modified polypeptides are therapeutics.

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