Factor VII polypeptides that are modified and uses thereof

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专利权人:

Edwin L. Madison;Christopher Thanos

发明人:

Edwin L. Madison,Christopher Thanos

申请号：

US12384915

公开号：

US08519103B2

申请日:

2009.04.10

申请国别(地区):

US

年份:

2013

代理人:

摘要：

Modified factor VII polypeptides and uses thereof are provided. Such modified FVII polypeptides include Factor VIIa and other forms of Factor VII. Among modified FVII polypeptides provided are those that have altered activities, typically altered procoagulant activity, including increased procoagulant activities. Hence, such modified polypeptides are therapeutics.

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