ACID ADDITION SALTS, HYDRATES AND POLYMORPHS OF 5-(2,4-DIHYDROXY-5-ISOPROPYL-PHENYL)-4-(4-MORPHOLIN-4-YLMETHYL-PHENYL)-ISOXAZOLE-3-CARBOXYLIC ACID ETHYLAMIDE AND FORMULATIONS COMPRISING THESE FORMS
The present invention relates to 5-(2,4-dihydroxy-5-isopropyl-phenyl)-the new salt form, particularly its mesylate, hydrochlorate, tartrate, phosphate and hemifumarate of 4-(4-morpholine-4-ylmethyl-phenyl)-different azoles-3-formic acid buserelin The invention still further relates to the crystal form of this type of salt The polymorph that relates to 5-(2,4-dihydroxy-5-isopropyl-phenyl)-4-(4-morpholine-4-ylmethyl-phenyl)-different azoles-3-formic acid buserelin The hydrate and the polymorph that relate to above-mentioned new salt form Relate to above-mentioned new salt form and be used for the treatment of purposes in the medicine of Hsp90 disorder mediated in preparation Relate to the method for using new salt form treatment Hsp90 disorder mediated Relate to the preparation that comprises this type of salt form, particularly be fit to the aqueous solution that intravenous is used And relate to the amber glass container that is filled with this type of preparation.
