您的位置: 首页 > 农业专利 > 详情页

AN IMPROVED PROCESS FOR THE PREPARATION OF MEBEVERINE AND ITS INTERMEDIATE
专利权人:
发明人:
MORTHALA RAGHAVENDAR RAO,GHARPURE MILIND,KUMBHAR AJAY,SINORE SANDIP,KADAM SANTOSH,KRISHNMURTHY DHILEEPKUMAR,KRISHNMURTHY DHILEEPKUMAR
申请号:
IN646/MUM/2015
公开号:
IN2015MU00646A
申请日:
2015.02.27
申请国别(地区):
IN
年份:
2017
代理人:
摘要:
The present invention provides an improved process for the preparation of Mebeverine [4-(ethyl(l-(4-methoxyphenyl)propan-2- yl)amino)butyl 3,4-dimethoxybenzoate] or a pharmaceutically acceptable salt thereof and its intermediates. The process comprises use of compound (VI), obtained from compound (V) for the preparation of 4-(ethyl(l-(4-methoxyphenyl)propan-2-yl)amino)butyl 3,4- dimethoxybenzoate, a compound of formula (I) or a pharmaceutically acceptable salt thereof. The process also comprises the preparation of 4-(ethyl(l-(4-methoxyphenyl)propan-2-yl)amino)butyl acetate, compound (V), comprising reacting compound (Ilia) with compound (IV) and further involves insitu conversion of (V) to the compound (VI).
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

意 见 箱

匿名:登录

个人用户登录

找回密码

第三方账号登录

忘记密码

个人用户注册

必须为有效邮箱
6~16位数字与字母组合
6~16位数字与字母组合
请输入正确的手机号码

信息补充