SELS DE 2-FLUORO-N-MÉTHYL-4-[7-(QUINOLÉIN-6-YL-MÉTHYL)- IMIDAZO[1,2-B][1,2,4]TRIAZIN-2-YL]BENZAMIDE ET PROCÉDÉS ASSOCIÉS À LEUR PRÉPARATION

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专利权人:

Incyte Holdings Corporation

发明人:

申请号：

EP09751439.2

公开号：

EP2300455B1

申请日:

2009.05.20

申请国别(地区):

EP

年份:

2017

代理人:

摘要：

The present invention is directed to dihydrochloric acid and dibenzenesulfonic acid salts of the c-Met kinase inhibitor 2-fluoro-N-methyl-4-[7-(quinolin-6-ylmethyl)-imidazo[1,2-b][1,2,4]triazin-2-yl]benzamide, and pharmaceutical compositions thereof, useful in the treatment of cancer and other diseases related to the dysregulation of kinase pathways. The present invention further relates to processes and intermediates for preparing 2-fluoro-N-methyl-4-[7-(quinolin-6-ylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl]benzamide, and salts thereof.

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