SELS DE 2-FLUORO-N-METHYL-4-[7-(QUINOLEIN-6-YL-METHYL)- IMIDAZO[1,2-B][1,2,4]TRIAZIN-2-YL]BENZAMIDE ET PROCEDES ASSOCIES A LEUR PREPARATION

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专利权人:

INCYTE CORPORATION

发明人:

WENG, LINGKAI,QIAO, LEI,ZHOU, JIACHENG,LIU, PINGLI,PAN, YONGCHUN

申请号：

CA2724742

公开号：

CA2724742C

申请日:

2009.05.20

申请国别(地区):

CA

年份:

2016

代理人:

摘要：

The present invention is directed to dihydrochloric acid and dibenzenesulfonicacid salts of the c-Met kinase inhibitor2-fluoro-N-methyl-4-[7-(quinolin-6-ylmethyl)-imidazo[1,2-b][1,2,4]triazin-2-yl]benzamide, and pharmaceutical compositionsthereof, useful in the treatment of cancer and other diseases related to thedysregulation of kinase pathways. The presentinvention further relates to processes and intermediates for preparing 2-fluoro-N-methyl-4-[7-(quinolin-6-ylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl]benzamide, and salts thereof.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/