2-Fluoro-n-methyl-4- [7- (quinolin-6-yl-methyl) -imidazo [1,2-b] [1,2,4] triazin-2-yl] benzamide salts and related processes their preparation

• 收藏
• 分享

专利权人:

Incyte Corporation

发明人:

Jiacheng Zhou,Lei Qiao,Lingkai Weng,Pingli Liu,Yongchun Pan

申请号：

BRPI0912882

公开号：

BRPI0912882A2

申请日:

2009.05.20

申请国别(地区):

BR

年份:

2017

代理人:

摘要：

The present invention is directed to dihydrochloric acid and dibenzenesulfonic acid salts of the c-Met kinase inhibitor 2-fluoro-N-methyl-4-[7-(quinolin-6-ylmethyl)-imidazo[1,2-b][1,2,4]triazin-2-yl]benzamide, and pharmaceutical compositions thereof, useful in the treatment of cancer and other diseases related to the dysregulation of kinase pathways. The present invention further relates to processes and intermediates for preparing 2-fluoro-N-methyl-4-[7-(quinolin-6-ylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl]benzamide, and salts thereof.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/