WATKINS, DAVID,OKSCHE, ALEXANDER,SMITH, KEVIN,MANSIKKA, HEIKKI,BAILEY, PAUL
申请号:
PH12015502655
公开号:
PH12015502655A1
申请日:
2015.11.27
申请国别(地区):
PH
年份:
2016
代理人:
摘要:
The present invention provides a method of providing pain relief in a human subject in need thereof comprising administering (R)-dihydroetorphine to said subject, wherein said (R)-dihydroetorphine is administered in a dose of at least 0.01 mg/kg, preferably at least 0.05 mg/kg, and the level of respiratory depression in said subject is 65 or less pcnt relative to the baseline level pre-administration of (R)-dihydroetorphine.