The present invention relates to neurological disorders and treatment of epilepsy, seizures and alcoholism. In one embodiment, the present invention provides a method of treating the frequency of epileptic seizures in an subject by administering a therapeutically effective dosage of a composition comprising creatine and/or phosphocreatine. In another embodiment, the present invention provides a method of treating alcoholism by administering a composition comprising creatine and/or phosphocreatine.