Methods of treating alcohol intoxication, alcohol use disorders and alcohol abuse which comprise the administration of dihydromyricetin

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专利权人:

The Regents of the University of California

发明人:

Liang, Jing,Olsen, Richard W.,Spigelman, Igor

申请号：

AU2011293556

公开号：

AU2011293556A1

申请日:

2011.08.23

申请国别(地区):

AU

年份:

2013

代理人:

摘要：

Disclosed herein are methods for treating alcohol intoxication, alcohol use disorders and alcohol abuse which comprise the administration of dihydromyricetin. As disclosed herein, dihydromyricetin potentiates the activity of GABAARs having the alpha4-beta-delta subunit which is associated with the effects of ethanol, antagonizes the actions of ethanol on the GABAARs, acts on the benzodiazepine sites of GABAARs, and inhibits, reduces and/or reverses some or all of the GABAAR plasticity which is caused by exposure to ethanol.

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中国工程科技知识中心

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http://www.ckcest.cn/home/