AAAADisclosed herein are methods for treating alcohol intoxication alcohol use disorders and alcohol abuse which comprise the administration of dihydromyricetin. As disclosed herein dihydromyricetin potentiates the activity of GABARs having the alpha4 beta delta subunit which is associated with the effects of ethanol antagonizes the actions of ethanol on the GABARs acts on the benzodiazepine sites of GABARs and inhibits reduces and/or reverses some or all of the GABAR plasticity which is caused by exposure to ethanol.
