Harald WEINSTABL,Andreas GOLLNER,Juergen RAMHARTER,Tobias WUNBERG
申请号:
US14790032
公开号:
US20160000764A1
申请日:
2015.07.02
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present invention relates to compounds of formula (I)wherein the groups R1 to R3, R7, U, V, W, X, Y, n and q are as defined herein, their use as inhibitors of MDM2-p53 interaction, pharmaceutical compositions which contain compounds of this kind, their use as medicaments, especially as agents for treatment and/or prevention of oncological diseases and synthetic intermediates.