The invention provides crystalline forms of biphenyl-2-ylcarbamic acid 1-(2-{[4-(4-carbamoylpiperidin-1-ylmethyl)benzoyl]methylamino}ethyl)piperidin-4-yl ester, and pharmaceutically acceptable solvates thereof. The crystalline form can be a freebase, or a salt such as a diphosphate, monosulfate or dioxalate salt. The invention also provides pharmaceutical compositions comprising these crystalline compounds or prepared using these compounds； processes and intermediates for preparing the crystalline compounds； and methods of using these compounds to treat a pulmonary disorder.本發明提供聯苯-2-基胺基甲酸1-(2-{[4-(4-胺甲醯基哌啶-1-基甲基)苄醯基]甲胺基}乙基)哌啶-4-基酯之晶形及其醫藥學上可接受之溶劑合物。該晶形可為游離鹼或諸如二磷酸鹽、單硫酸鹽或二草酸鹽之鹽。本發明亦提供包含該等結晶化合物或使用該等化合物製備之醫藥組合物；製備該等結晶化合物之方法及中間體；及使用該等化合物於治療肺病之方法。
