SANDANAYAKA, Vincent P.,SHACHAM, Sharon,McCAULEY, Dilara,SHECHTER, Sharon
申请号：
AU2020203121
公开号：
AU2020203121A1
申请日:
2020.05.12
申请国别(地区):
AU
年份:
2020
代理人:
摘要：
#$%^&*AU2020203121A120200528.pdf#####ABSTRACT OF THE INVENTION The invention generally relates to nuclear transport modulators, e.g., CRM1 inhibitors, and more particularly to a compound represented by structural formula I: N-N NH / >； O N-R2 F3C NR R3 CF3 or a pharmaceutically acceptable salt thereof, wherein the values and alternative values for the variables are as defined and described herein. The invention also includes the synthesis and use of a compound of structural formula I, or a pharmaceutically acceptable salt or composition thereof, e.g., in the treatment, modulation and/or prevention of physiological conditions associated with CRM1 activity. (116100401):JIN
