SANDANAYAKA, Vincent P.,SHACHAM, Sharon,McCAULEY, Dilara,SHECHTER, Sharon
申请号：
AU2018202441
公开号：
AU2018202441A1
申请日:
2018.04.06
申请国别(地区):
AU
年份:
2018
代理人:
摘要：
#$%^&*AU2018202441A120180426.pdf#####ABSTRACT OF THE INVENTION The invention generally relates to nuclear transport modulators, e.g., CRM1 inhibitors, and more particularly to a compound represented by structural formula I: N-N NH / >；o N-R2 F3 N R CF, or a pharmaceutically acceptable salt thereof, wherein the values and alternative values for the variables are as defined and described herein. The invention also includes the synthesis and use of a compound of structural formula I, or a pharmaceutically acceptable salt or composition thereof, e.g., in the treatment, modulation and/or prevention of physiological conditions associated with CRM1 activity. (1161OO4_o):N
