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Sulfonamide compound
专利权人:
Rintaro Yamada
发明人:
Rintaro Yamada,Minoru Seto
申请号:
US12526000
公开号:
US08415372B2
申请日:
2007.02.27
申请国别(地区):
US
年份:
2013
代理人:
摘要:
A compound represented by the formula (1) [A represents a nitrogen-containing saturated ring m represents an integer of 0 to 2 n represents an integer of 1 to 4 G1 represents hydrogen atom, chlorine atom, hydroxyl group, an alkoxy group, or amino group G2 represents a halogen atom, hydroxyl group, cyano group, carboxy group, an alkyl group, an alkenyl group, and the like G3 represents hydrogen atom, a halogen atom, hydroxyl group, cyano group, carboxy group, an alkyl group, an alkenyl group, and the like G4 represents hydroxyl group, or —N(R1)(R2) (R1 and R2 represent hydrogen atom, an alkyl group, an aralkyl group, an alkenyl group, an alkynyl group, or a saturated heterocyclic group) G5 is a substituent on a ring-constituting carbon atom of A, and represents hydrogen atom, fluorine atom, or an alkyl group] or a salt thereof, or a derivative thereof that is a prodrug, which potently inhibits Rho kinase.
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