LO, YA CHIN,罗雅勤,羅雅勤,LIANG, HSIANG FA,梁祥发,梁祥發,WEI, MING CHENG,魏明正,魏明正,LU, MAGGIE J. M.,吕瑞梅,呂瑞梅,LIN, MIN YING,林敏英,林敏英,LIU, CHIH PENG,刘志鹏,劉志鵬,LIU, CHUN MIN,刘俊旻,劉俊旻,TSENG, HSIANG WEN,曾湘文,曾湘文,TENG, TSE MIN
申请号：
TW102138398
公开号：
TWI482634B
申请日:
2013.10.24
申请国别(地区):
TW
年份:
2015
代理人:
摘要：
The invention provides a biomedical composition, including: a hyaluronic acid a modified histidine and a polymer or C4-C20alkane, wherein the modified histidine and the polymer or C4-C20alkane are grafted to at least one alcohol group of the hyaluronic acid to get along with the hyaluronic acid to form a hyaluronic acid derivative, wherein a graft ratio of the modified histidine is about 1-100%, and a graft ratio of the polymer or the C4-C20alkane is about 0-40%.本發明提供一種生醫組合物,包括:一透明質酸;一經修飾之組胺酸;以及一聚合物或C4-C20烷類,其中該經修飾之組胺酸,與該聚合物或C4-C20烷類,接枝於該透明質酸之至少一個一級羥基上以與該透明質酸形成一透明質酸衍生物,且其中該經修飾之組胺酸之接枝率為約1-100%,而該聚合物或C4-C20烷類之接枝率為約0-40%。
