KUFER, PETER,HOFFMANN, PATRICK,MUNZ, MARKUS,KLINGER, MATTHIAS,DOPFER, ELAINE-PASHUPATI,NAHRWOLD, ELISABETH
申请号：
CA2952540
公开号：
CA2952540A1
申请日:
2015.07.31
申请国别(地区):
CA
年份:
2016
代理人:
摘要：
The present invention provides to a bispecific single chain antibody construct binding to a target cell surface antigen via a first binding domain and to the T cell surface antigen CD3 via a second binding domain, the construct comprising two FcRn binding peptides. Moreover, the invention provides a nucleic acid molecule encoding the antibody construct, a vector comprising said nucleic acid molecule and a host cell transformed or transfected with said vector. Furthermore, the invention provides a process for the production of the antibody construct of the invention, a medical use of said antibody construct and a kit comprising said antibody construct.
