A handheld sanitizing device with a housing having an internal passageway with an opening at a first end of the internal passageway and at least one radiation emitting device capable of emitting radiation that can destroy microorganisms at a second end of the internal passageway. The internal passageway includes a reflective material over at least a portion. Preferably the radiation emitting device comprises an LED capable of emitting UV-C light. In some embodiments, the device is a key fob sized device. The device may also be sized to house a cellular phone.