KANG, Heun Soo,KIM, Hye Mi,SONG, Ji Eun,KIM, Myoung Jin,CHOI, Ki Hang
申请号：
EP18848372
公开号：
EP3674305A1
申请日:
2018.08.23
申请国别(地区):
EP
年份:
2020
代理人:
摘要：
The present invention relates to a real-time fluorescence imaging sensor for measuring glutathione in cell organelles and a method for fabricating the same. More specifically, the present invention relates to a novel compound for measuring glutathione in cell organelles, a method for preparing the novel compound, a real-time fluorescence imaging sensor for measuring glutathione in cell organelles, which comprises the novel compound, a method for fabricating the imaging sensor, and a method of measuring glutathione in cell organelles by use of the imaging sensor.When the composition comprising the compound according to the present invention is used, it can measure the antioxidant activity of the organelle mitochondria or Golgi apparatus in living cells, particularly stem cells, and can screen highly active stem cells based on the results obtained by measuring the antioxidant activity of the cell organelle.
