Piperidine substituted tricyclic pyrazolo[1,5-a]pyrimidine derivatives with inhibitory activity on the replication of the respiratory syncytial virus (RSV)
Abdellah Tahari,Sandrine Marie Helene Vendeville,Tim Hugo Maria Jonckers,Pierre Jean-Marie Bernard Raboisson,Samuël Dominique Demin,Lili Hu
申请号:
US15534458
公开号:
US10131673B2
申请日:
2015.12.07
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The invention concerns novel substituted tricyclic pyrazolo pyrimidine compounds of formula (I-a) or (I-b) having antiviral activity, in particular, having an inhibitory activity on the replication of the respiratory syncytial virus (RSV). The invention further concerns the preparation of such novel compounds, compositions comprising these compounds, and the compounds for use in the treatment of respiratory syncytial virus infection.