Compounds of the following formula are provided for use with kinases:wherein the variables are as defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds; methods and intermediates useful for making the compounds; and methods of using said compounds.本發明係提供用於激酶之下式化合物:其中變數均如本文定義。亦提供者為包含此種化合物之醫藥組合物、套件及製造物件;可用於製造該化合物之方法與中間物;及使用該化合物之方法。