KIM, JAE SOO,金载洙,金載洙,KWON, SOON CHANG,权纯昌,權純昌,PARK, SANG JIN,朴相珍,朴相珍
申请号：
TW108122646
公开号：
TW201938175A
申请日:
2017.06.16
申请国别(地区):
TW
年份:
2019
代理人:
摘要：
The present invention relates to a hyaluronic acid microstructure having excellent solubility characteristics. More specifically, the present invention relates to a biodegradable microstructure comprising cross-linked hyaluronic acid and having excellent solubility characteristics during skin penetration. When the microstructure of the present invention is penetrated into the skin, the solubility characteristics in the skin are excellent, the dissolution rate in the skin can be easily controlled according to the content ratio of the cross-linked hyaluronic acid, and, while effective ingredients provided on the microstructure can be stably delivered into the skin, the release rate of the provided effective ingredients can be easily controlled, and thus the present invention can be used as a transdermal delivery system for pharmaceutically active materials or skin improvement materials.本發明涉及溶解特性優秀的透明質酸微結構體。更詳細地，本發明涉及包含交聯透明質酸且滲透皮膚時溶解特性優秀的可生物降解的微結構體。在本發明的微結構體滲透皮膚情況下，不僅在皮膚內溶解特性優秀，而且可根據交聯透明質酸的含量比率容易地調節皮膚內溶解速度，還可向皮膚內穩定地傳遞裝載於微結構體的有效成分的同時容易地調節有效成分的釋放速度，因此可有用地用作藥理活性物質或皮膚改善物質的經皮型載體。
