Nathan P. Myhrvold;Eric C. Leuthardt;Lowell L. Wood, Jr.;Robert Langer;Roderick A. Hyde;Muriel Y. Ishikawa;Elizabeth A. Sweeney;Edward K. Y. Jung
发明人:
Roderick A. Hyde,Muriel Y. Ishikawa,Edward K. Y. Jung,Robert Langer,Eric C. Leuthardt,Nathan P. Myhrvold,Elizabeth A. Sweeney,Lowell L. Wood, Jr.
申请号：
US12660928
公开号：
US08167871B2
申请日:
2010.03.05
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Devices, systems, and methods are described herein for controlling the level of one or more target cell types in the blood fluid and/or lymph fluid of a vertebrate subject. Devices and systems are provided that include a body defining at least one lumen configured for fluid flow； at least one controllable flow barrier to the at least one lumen； one or more sensor configured to detect one or more target cell types in blood fluid or lymph fluid of a vertebrate subject； at least one treatment region disposed within the at least one lumen； at least one reactive component disposed in the at least one treatment region, the at least one reactive component configured to modulate a physiological effect of the one or more target cell types in the vertebrate subject； and at least one controller in communication with the one or more sensor and in communication with the at least one controllable flow barrier to the at least one lumen； wherein the at least one controller is configured to open or close the at least one controllable flow barrier in response to the one or more sensor.
