Nathan P. Myhrvold;Eric C. Leuthardt;Lowell L. Wood, Jr.;Robert Langer;Roderick A. Hyde;Muriel Y. Ishikawa;Elizabeth A. Sweeney;Edward K. Y. Jung
发明人:
Roderick A. Hyde,Muriel Y. Ishikawa,Edward K. Y. Jung,Robert Langer,Eric C. Leuthardt,Nathan P. Myhrvold,Elizabeth A. Sweeney,Lowell L. Wood, Jr.
申请号:
US12802854
公开号:
US08172826B2
申请日:
2010.06.14
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Devices, systems, and methods are described herein for controlling the level of one or more target cell types in the blood fluid and/or lymph fluid of a vertebrate subject. Devices and systems are provided that include a body defining at least one lumen configured for fluid flow; at least one controllable flow barrier to the at least one lumen; one or more sensor configured to detect one or more target cell types in blood fluid or lymph fluid of a vertebrate subject; at least one treatment region disposed within the at least one lumen; at least one reactive component disposed in the at least one treatment region, the at least one reactive component configured to modulate a physiological effect of the one or more target cell types in the vertebrate subject; and at least one controller in communication with the one or more sensor and in communication with the at least one controllable flow barrier to the at least one lumen; wherein the at least one controller is configured to open or close the at least one controllable flow barrier in response to the one or more sensor.