The Brigham and Women's Hospital, Inc.;President and Fellows of Harvard College;Massachusetts Institute of Technology
发明人:
Georg Stary,Aleksandar Filip Radovic-Moreno,Pamela A. Basto,Michael N. Starnbach,Robert S. Langer,Omid C. Farokhzad,Ulrich Von Andrian
申请号:
US16679920
公开号:
US20200215179A1
申请日:
2019.11.11
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Provided herein are new compositions including an inactivated pathogen and one or more adjuvant-loaded polymeric nanoparticles, wherein the adjuvant-loaded nanoparticles are bound to the inactivated pathogen. These compositions are useful for preventing and/or treating diseases caused by the specific pathogens, especially when administered to a subject's mucosal membranes.