PRESIDENT AND FELLOWS OF HARVARD COLLEGE;MASSACHUSETTS INSTITUTE OF TECHNOLOGY;THE BRIGHAM AND WOMEN'S HOSPITAL, INC.
发明人:
STARY, GEORG,RADOVIC-MORENO, ALEKSANDAR FILIP,BASTO, PAMELA A.,STARNBACH, MICHAEL N.,LANGER, ROBERT,FAROKHZAD, OMID C.,ANDRIAN, ULRICH VON
申请号:
CA2902560
公开号:
CA2902560A1
申请日:
2014.03.14
申请国别(地区):
CA
年份:
2014
代理人:
摘要:
Provided herein are new compositions including an inactivated pathogen and one or more adjuvant-loaded polymeric nanoparticles, wherein the adjuvant-loaded nanoparticles are bound to the inactivated pathogen. These compositions are useful for preventing and/or treating diseases caused by the specific pathogens, especially when administered to a subject's mucosal membranes.