Preparation containing 6,7-unsaturated-7-carbamoylmorphinan derivative

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专利权人:

塩野義製薬株式会社

发明人:

真下 全,一尾 俊司

申请号：

JP2014515611

公开号：

JP5818219B2

申请日:

2013.05.13

申请国别(地区):

JP

年份:

2015

代理人:

摘要：

The solid preparation which improved the dissolution profile and the stability of the 6,7-unsaturation-7-carbamoyl morphinan derivative is provided. When 6,7-unsaturation-7-carbamoyl morphinan derivative, croscarmellose sodium and ferric oxide were contained, not titanium oxide in the solid preparations and the coating solid preparations, a dissolution rate after 15 minutes of the dissolution test is more than 85%, and stability, particularly, light stability can be improve.

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