JUNG-SANG PARK,SOON-HOE KIM,WEON-BIN IM,CHONG-HWAN CHO,SUN-HO CHOI,MI-YEON KIM,SUNG-HAK CHOI,MIN-JUNG LEE,KANG-HUN CHO
申请号：
PT14831249
公开号：
PT3029026T
申请日:
2014.07.17
申请国别(地区):
PT
年份:
2019
代理人:
摘要：
The present invention provides novel biphenyl derivatives, isomers thereof, or pharmaceutically acceptable salts thereof, methods for preparing the same, and a pharmaceutical composition containing the same. The novel biphenyl derivatives, isomers thereof, or pharmaceutically acceptable salts thereof, as disclosed in the present invention, act as muscarinic M3 receptor antagonists, and thus are useful for the prevention or treatment of a disease selected from the group consisting of chronic obstructive pulmonary disease, asthma, irritable bowel syndrome, urinary incontinence, rhinitis, spasmodic colitis, chronic cystitis, Alzheimer's disease, senile dementia, glaucoma, schizophrenia, gastroesophageal reflux disease, cardiac arrhythmia, and hyper-salivation syndromes.
