KIM, SOON-HOE,IM, WEON-BIN,CHO, CHONG-HWAN,CHOI, SUN-HO,PARK, JUNG-SANG,KIM, MI-YEON,CHOI, SUNG-HAK,LEE, MIN-JUNG,CHO, KANG-HUN
申请号：
PH12016500197
公开号：
PH12016500197A1
申请日:
2016.01.28
申请国别(地区):
PH
年份:
2016
代理人:
摘要：
The present invention provides a novel biphenyl derivative, or an isomer or pharmaceutically acceptable salt thereof, a method for preparing the same, and a pharmaceutical composition containing the same. The novel biphenyl derivative, or the isomer or pharmaceutically acceptable salt thereof according to the present invention acts as a muscarinic M3 receptor antagonist, and thus can be useful for the prevention or treatment of a disease selected from the group consisting of chronic obstructive pulmonary disease, asthma, irritable bowel syndrome, urinary incontinence, rhinitis, spasmodic colitis, chronic cystitis, Alzheimer's disease, senile dementia, glaucoma, schizophrenia, gastroesophogeal reflux disease, cardiac arrhythmia, and hyper salivation syndrome.
