Disclosed are a smart headphone device (400) personalization system and a method for using the system. A user downloads a headphone personalization application program unit (200) from the server device (100) for installation in a mobile device (300). The mobile device (300) and the smart headphone device (400) are paired. The user enters corresponding data through the register module (21) of the mobile device (300). The user wears the smart headphone device (400) to allow a hearing inspection module (22) of the mobile device (300) to inspect hearing capabilities of left and right ears of the user and generate an inspection result. The automatic compensation unit (44) of the smart headphone device (400) may automatically carry out compensation according to the inspection result. Then, the manual compensation module (23) of the mobile device (300) further carries out compensation. Finally, the user adjusts the sound effect mode by using the preference setting module (24) of the mobile device (300) to complete personalization of the smart headphone device (400).