Brittle, Elizabeth E.,Friedman, Harvey,Wang, Fushan
申请号：
AU2007292905
公开号：
AU2007292905B2
申请日:
2007.09.07
申请国别(地区):
AU
年份:
2013
代理人:
摘要：
This invention provides methods of vaccinating a subject against a Herpes Simplex Virus (HSV) infection and disorders and symptoms associated with same, and impeding, inhibiting, reducing the incidence of, and suppressing HSV infection, neuronal viral spread, formation of zosteriform lesions, herpetic ocular disease, herpes-mediated encephalitis, and genital ulcer disease in a subject, comprising the step of contacting the subject with a mutant strain of the HSV, containing an inactivating mutation in a gene encoding a gE, gl, Us9, or other proteins.
