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HSV-1 and HSV-2 vaccines and methods of use thereof
专利权人:
Harvey Friedman;Fushan Wang;Elizabeth E. Zumbrun
发明人:
Harvey Friedman,Elizabeth E. Zumbrun,Fushan Wang
申请号:
US12440223
公开号:
US08871223B2
申请日:
2007.09.07
申请国别(地区):
US
年份:
2014
代理人:
摘要:
This invention provides methods of vaccinating a subject against a Herpes Simplex Virus (HSV) infection and disorders and symptoms associated with same, and impeding, inhibiting, reducing the incidence of, and suppressing HSV infection, neuronal viral spread, formation of zosteriform lesions, herpetic ocular disease, herpes-mediated encephalitis, and genital ulcer disease in a subject, comprising the step of contacting the subject with a mutant strain of the HSV, containing an inactivating mutation in a gene encoding a gE, gI, Us9, or other proteins.
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中国工程科技知识中心
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