TECHNIQUE AUTOMATISÉE IMMÉDIATE DE CRIBLAGE, DE DIAGNOSTIC ET DE CLASSIFICATION POUR LA MALADIE D'ALZHEIMER UTILISANT UN SIGNAL D'IMAGERIE PAR RÉSONANCE MAGNÉTIQUE PROVENANT D'UN CONTOUR DE LA ZONE VENTRICULAIRE DU CERVEAU
DEPARTMENT OF BIOTECHNOLOGY;NATIONAL BRAIN RESEARCH CENTRE
发明人:
ROY, PRASUN,RALLABANDI, SUBRAMANYAM, V.P.
申请号：
EP09824502
公开号：
EP2355703A4
申请日:
2009.02.10
申请国别(地区):
EP
年份:
2014
代理人:
摘要：
The invention relates to a fully automated screening, diagnosis and classification technique for Alzheimer's disease using magnetic resonance imaging signals from the ventricular zone contour of the brain to get a fundamental index of brain deterioration comprising the steps: -obtaining a gray scale MRI image of the brain region； -applying a contour edge-detecting algorithm to the image； -employing a grid covering method for calculating a first order metric index of ventricular zone contour； -superimposing metric square grids of increasing edge length to the binary contour image and counting the metric grid squares； -plotting the logs of metric grid squares against the logs of edge lengths, wherein the gradient of the plot is the linear topological metric index.
