Byung Yeoup Chung,Tae Hoon Kim,Seung Sik Lee,Hyoungwoo Bai,Sungbeom Lee,Chul Hong Park
申请号：
US14693795
公开号：
US09328123B2
申请日:
2015.04.22
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The present invention relates to rotenone derivatives and a use of the same. Particularly, the present inventors identified rotenoisin A and B which are compounds with no toxicity and which are prepared by irradiation with gamma rays onto rotenone as represented by the following formula 1. It was further confirmed that the rotenone derivatives significantly inhibited pancreatic lipase activity and preadipocyte differentiation. The rotenone derivatives of the present invention can be effectively used as a composition for the prevention and treatment of obesity and as a composition for health functional food for the prevention and improvement of obesity:(In formula 1, R1 and R2 are as defined in this description).
