RIKEN;SUMITOMO CHEMICAL COMPANY LIMITED;SUMITOMO DAINIPPON PHARMA CO. LTD.
发明人:
申请号：
IL25185617
公开号：
IL251856D0
申请日:
2017.04.23
申请国别(地区):
IL
年份:
2017
代理人:
摘要：
The present invention provides a method for producing retinal cells or a retinal tissue, comprising the following steps (1) - (3): (1) a first step of culturing human pluripotent stem cells in the absence of feeder cells and in a medium comprising a factor for maintaining undifferentiated state, (2) a second step of culturing the pluripotent stem cells obtained in the first step in suspension in the presence of a Sonic hedgehog signal transduction pathway activating substance to form a cell aggregate, and (3) a third step of culturing the aggregate obtained in the second step in suspension in the presence of a 1) a BMP signal transduction pathway activating substance to obtain an aggregate containing retinal cells or a retinal tissue.
