JUNG SUNG YOUB,WOO YOUNG EUN,LIM SE YOUNG,CHOI IN YOUNG,LEE JAE HO,KWON SE CHANG,MOON SUNG HWAN,LIU JIAWANG
申请号：
IN2714/DELNP/2014
公开号：
IN2014DN02714A
申请日:
2014.04.04
申请国别(地区):
IN
年份:
2015
代理人:
摘要：
THE PRESENT INVENTION RELATES TO AN ANTI CANCER PHARMACEUTICAL COMPOSITION COMPRISING AN INTERFERON ALPHA OR A POLYMER CONGUGATE THEREOF AND USE THEREOF IN THE TREATMENT OF CANCER BY CO ADMINISTRATION WITH ANTI CANCER AGENTS. THE INTERFERON ALPHA CONJUGATE OF THE PRESENT INVENTION SHOWS A LONGER HALF LIFE AND A MORE EXCELLENT ANTI CANCER ACTIVITY THAN THE CONVENTIONAL INTERFERON ALPHA AND IN PARTICULAR ITS CO ADMINISTRATION WITH AN ANTI CANCER AGENT SUCH AS GEMCITABINE HAS SYNERGISTIC INHIBITORY EFFECTS ON CANCER CELL GROWTH AND PROLIFERATION SO AS TO EXHIBIT A REMARKABLY EXCELLENT ANTI CANCER ACTIVITY. FURTHER THE ANTI CANCER PHARMACEUTICAL COMPOSITION OF THE PRESENT INVENTION HAS EXCELLENT HALF LIFE AND ANTI CANCER ACTIVITY TO GREATLY REDUCE ADMINISTRATION FREQUENCY. CO ADMINISTRATION OF AN ANTI CANCER AGENT AND THE INTERFERON ALPHA CONJUGATE HAVING EXCELLENT ANTI CANCER ACTIVITY REDUCES ADMINISTRATION DOSE OF ANTI CANCER AGENT SO AS TO REDUCE SIDE EFFECTS OF ANTI CANCER AGENT AND INCREASE TREATMENT COMPLIANCE OF PATIENT.
