THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA;DUKE UNIVERSITY;THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL
发明人:
Barton F. Haynes,Hua-Xin Liao,Li-Hua Ping,Ronald Swanstrom,Beatrice H. Hahn,George M. Shaw
申请号:
US14106461
公开号:
US10561725B2
申请日:
2013.12.13
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present invention relates, in general, to an immunogen for HIV vaccination and, in particular, to a method of inducing the production of protective anti-HIV antibodies by targeting B cell germline and clone intermediates using a combination of HIV envelope and non-HIV immunogens. The invention also relates to compositions suitable for use in such a method.