Barton F. Haynes,Hua-Xin Liao,Georgia Tomaras,Thomas B. Kepler,Kwan-Ki Hwang,S.Munir Alam,Yang Liu,T. Matt Holl,Guang Yang,Garnett Kelsoe,Mattia Bonsignori
申请号:
US13581157
公开号:
US20120321699A1
申请日:
2011.02.25
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention relates, in general, to an immunogen for HIV vaccination and, in particular, to a method of inducing the production of protective anti-HIV antibodies by targeting B cell germline and clone intermediates using a combination of HIV envelope and non-HIV immunogens. The invention also relates to compositions suitable for use in such a method.