UNIVERSITY OF MARYLAND, OFFICE OF TECHNOLOGY COMMERCIALIZATION;REMEDIUM TECHNOLOGIES, INC.; OFFICE OF TECHNOLOGY COMMERCIALIZATION;THE GENERAL HOSPITAL CORPORATION;UNIVERSITY OF MARYLAND
发明人:
DIEHN, KEVIN,DOWLING, MATTHEW,RAGHAVAN, SRINIVASA R.,KING, DAVID R.
申请号：
CA2914610
公开号：
CA2914610A1
申请日:
2014.03.13
申请国别(地区):
CA
年份:
2014
代理人:
摘要：
A hemostatic putty for treatment of a variety of wounds topographies, including but not limited to highly three dimensional wounds, for example gunshot wounds and impalements, is disclosed. The putty is comprised of a matrix polymer weakly crosslinked or not crosslinked such that a viscoelastic matrix is formed. The viscoelastic nature of the putty is tunable by the composition and enables the putty to conform to a variety of wound topographies. Likewise, a hemostatic polymer, for example chitosan or hydrophobically modified chitosan, is included in this matrix to impart hemostatic properties and tissue adhesive on the putty. The hemostatic polymers disclosed prevent microbial infection and are suitable for oxygen transfer required during normal wound metabolism.
