Tricyclic compounds having corticotropin-releasing factor antagonistic activity and pharmaceutical compositions containing them

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专利权人:

Kazuyoshi Aso

发明人:

Kazuyoshi Aso,Katsumi Kobayashi,Takafumi Takai,Takuto Kojima,Kazuyuki Tokumaru,Michiyo Mochizuki

申请号：

US12863851

公开号：

US08901141B2

申请日:

2009.01.21

申请国别(地区):

US

年份:

2014

代理人:

摘要：

There is provided a compound of the formula (I′): wherein X is a nitrogen or CRx, Rx is a hydrogen, etc., R1 is an optionally substituted hydrocarbon group, etc., R2 is an optionally substituted hydrocarbon group, etc., ring A is 5- to -8-membered heterocyclic ring, etc., and each of Y1, Y2 and Y3 is an optionally substituted carbon or a nitrogen, etc. or ‘a salt thereof or a prodrug thereof, which have CRF receptor antagonistic activity and use thereof.

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