Stefan Lindgren,Anders Carlsson,Anton Karlsson,Henrik Falkén,Gerhard Jobst
申请号:
US14611349
公开号:
US09420966B2
申请日:
2015.02.02
申请国别(地区):
US
年份:
2016
代理人:
摘要:
A measuring system for measuring the concentration of substances or analytes in a body fluid or in a body tissue comprises a microdialysis probe comprising a microdialysis membrane, the probe being adapted to be placed in blood or in tissue, a flow through sensor for analyzing a fluid having passed the microdialysis probe, a pump for pumping the fluid to and through the microdialysis probe and further to and through the sensor, and tubing connecting the pump to the microdialysis probe and the microdialysis probe to the sensor. The pump effects a flow rate in the system in the interval 0.2-15 microliters per minute. The sensor comprises a flow channel having a flow resistance or pressure drop adapted to the characteristics of the microdialysis membrane so as to eliminate, or at least substantially reduce, ultra filtering in the microdialysis membrane.