RUNTZ-SCHMITT, Valerie,SCHNIDER, Patrick,DOLENTE, Cosimo,FASCHING, Bernhard
申请号:
DK14815318
公开号:
DK3083633T3
申请日:
2014.12.16
申请国别(地区):
DK
年份:
2018
代理人:
摘要:
The present invention provides spiro-oxazolones, which act as V1a receptor modulators, and in particular as V1a receptor antagonists, their manufacture, pharmaceutical compositions containing them and their use as medicaments. The present compounds are useful as therapeutics acting peripherally and centrally in the conditions of inappropriate secretion of vasopressin, anxiety, depressive disorders, obsessive compulsive disorder, autistic spectrum disorders, schizophrenia, aggressive behavior and phase shift sleep disorders, in particular jetlag.