RUNTZ-SCHMITT, VALERIE,SCHNIDER, PATRICK,DOLENTE, COSIMO,FASCHING, BERNHARD
申请号：
CA2932063
公开号：
CA2932063A1
申请日:
2014.12.16
申请国别(地区):
CA
年份:
2015
代理人:
摘要：
The present invention provides spiro-oxazolones, which act as V1a receptor modulators, and in particular as V1a receptor antagonists, their manufacture, pharmaceutical compositions containing them and their use as medicaments. The present compounds are useful as therapeutics acting peripherally and centrally in the conditions of inappropriate secretion of vasopressin, anxiety, depressive disorders, obsessive compulsive disorder, autistic spectrum disorders, schizophrenia, aggressive behavior and phase shift sleep disorders, in particular jetlag.
